Practice CPSP FCPS I Paediatrics questions with answers and explanations.
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Anaplasia is loss of differentiation and cellular organisation in a malignant neoplasm.
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Amyloidosis is extracellular deposition of misfolded protein in a beta-pleated sheet configuration.
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Apoptosis is programmed cell death with cell shrinkage and minimal inflammation.
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Reed-Sternberg cell is a large atypical cell classically associated with Hodgkin lymphoma.
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Metaplasia is a reversible replacement of one mature cell type by another better suited to stress.
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Glomerular filtration rate is the volume of plasma filtered by all functioning glomeruli per unit time.
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Surfactant is a phospholipid-rich substance that lowers alveolar surface tension and helps prevent collapse.
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Bohr effect is reduced haemoglobin affinity for oxygen in tissues with increased carbon dioxide or acidity.
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Insulin is a pancreatic beta-cell hormone that promotes glucose uptake and storage and lowers blood glucose.
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Coagulative necrosis is a pattern of cell death with preserved tissue architecture, typical of ischaemia in solid organs except brain.
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Caseous necrosis is a friable cheese-like pattern of necrosis classically associated with tuberculosis.
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Granuloma is an organised collection of activated macrophages formed in response to persistent inflammation.
