Practice CPSP FCPS I Paediatrics questions with answers and explanations.
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Loading dose is an initial larger dose used to achieve a target concentration rapidly.
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ACE inhibitor is a drug class that reduces angiotensin II formation and may cause cough or hyperkalaemia.
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Beta blocker is a drug class that antagonises beta-adrenergic receptors and can reduce heart rate.
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Proton-pump inhibitor is a drug that irreversibly suppresses the gastric hydrogen-potassium ATPase.
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Naloxone is a competitive opioid receptor antagonist used to reverse opioid toxicity.
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Neonatal jaundice is yellow discoloration in a newborn caused by elevated bilirubin.
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Bronchiolitis is a viral lower-airway illness in infants causing cough, wheeze and increased work of breathing.
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Croup is an upper-airway viral illness characterised by barking cough and inspiratory stridor.
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Febrile seizure is a seizure associated with fever in a young child without central nervous system infection or another defined cause.
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Agonist is a ligand that binds to a receptor and activates it to produce a biological response.
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Competitive antagonist is a reversible receptor blocker whose effect can be overcome by increasing agonist concentration.
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First-pass metabolism is presystemic metabolism that reduces oral bioavailability before a drug reaches systemic circulation.
