Practice CPSP FCPS I Anaesthesiology questions with answers and explanations.
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Therapeutic index is a measure comparing toxic and effective doses and indicating a drug safety margin.
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Warfarin is an oral anticoagulant that inhibits vitamin-K dependent clotting factor synthesis.
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Insulin is a peptide hormone drug used to lower blood glucose and treat insulin deficiency.
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Aminoglycoside is an antibiotic class associated with nephrotoxicity and ototoxicity.
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Adverse drug reaction is a harmful and unintended response to a medicine used at normal doses.
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Agonist is a ligand that binds to a receptor and activates it to produce a biological response.
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Competitive antagonist is a reversible receptor blocker whose effect can be overcome by increasing agonist concentration.
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First-pass metabolism is presystemic metabolism that reduces oral bioavailability before a drug reaches systemic circulation.
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Half-life is the time required for the plasma concentration of a drug to fall by one half.
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Half-life is the time required for the plasma concentration of a drug to fall by one half.
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Therapeutic index is a measure comparing toxic and effective doses and indicating a drug safety margin.
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Loading dose is an initial larger dose used to achieve a target concentration rapidly.
