Practice NEB Dental Standard 3 questions with answers and explanations.
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Competitive antagonist is a reversible receptor blocker whose effect can be overcome by increasing agonist concentration.
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First-pass metabolism is presystemic metabolism that reduces oral bioavailability before a drug reaches systemic circulation.
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Half-life is the time required for the plasma concentration of a drug to fall by one half.
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Therapeutic index is a measure comparing toxic and effective doses and indicating a drug safety margin.
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Caseous necrosis is a friable cheese-like pattern of necrosis classically associated with tuberculosis.
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Granuloma is an organised collection of activated macrophages formed in response to persistent inflammation.
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Dysplasia is disordered epithelial growth with cytological atypia that may precede malignancy.
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Metaplasia is a reversible replacement of one mature cell type by another better suited to stress.
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Virchow triad is endothelial injury, abnormal blood flow and hypercoagulability as major contributors to thrombosis.
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Anaplasia is loss of differentiation and cellular organisation in a malignant neoplasm.
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Amyloidosis is extracellular deposition of misfolded protein in a beta-pleated sheet configuration.
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Apoptosis is programmed cell death with cell shrinkage and minimal inflammation.
