Practice Applied Pathology questions with answers and explanations.
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Reed-Sternberg cell is a large atypical cell classically associated with Hodgkin lymphoma.
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Atherosclerosis is intimal lipid-rich plaque formation in medium and large arteries.
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Coagulative necrosis is a pattern of cell death with preserved tissue architecture, typical of ischaemia in solid organs except brain.
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Caseous necrosis is a friable cheese-like pattern of necrosis classically associated with tuberculosis.
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Granuloma is an organised collection of activated macrophages formed in response to persistent inflammation.
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Dysplasia is disordered epithelial growth with cytological atypia that may precede malignancy.
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Metaplasia is a reversible replacement of one mature cell type by another better suited to stress.
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Virchow triad is endothelial injury, abnormal blood flow and hypercoagulability as major contributors to thrombosis.
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Anaplasia is loss of differentiation and cellular organisation in a malignant neoplasm.
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Amyloidosis is extracellular deposition of misfolded protein in a beta-pleated sheet configuration.
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Apoptosis is programmed cell death with cell shrinkage and minimal inflammation.
