Practice Genetics, Ethics & Research questions with answers and explanations.
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Blinding is keeping participants, clinicians or assessors unaware of assignment to reduce bias.
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Confidence interval is a range of values compatible with the observed data under a stated confidence level.
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Randomisation is allocation by chance to reduce selection bias and balance known and unknown confounders.
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Blinding is keeping participants, clinicians or assessors unaware of assignment to reduce bias.
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Confidence interval is a range of values compatible with the observed data under a stated confidence level.
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P value is a probability calculated under a null hypothesis for results at least as extreme as those observed.
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Type I error is rejecting a true null hypothesis.
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Type II error is failing to reject a false null hypothesis.
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Autonomy is respect for a person’s right to make informed decisions about their own care.
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Beneficence is an ethical duty to promote the patient’s welfare.
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Non-maleficence is an ethical duty to avoid causing unnecessary harm.
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Justice is fair distribution of benefits, burdens and healthcare resources.
