MCQ Collection
opra MCQs
Practice opra questions with answers and explanations.
Choose an option to check your answer.
A.
Positive predictive value depends on disease prevalence as well as test performance.
B.
It is independent of prevalence.
C.
It must be 100% when specificity is above 50%.
D.
It is always equal to sensitivity.
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Correct Answer: A. Positive predictive value depends on disease prevalence as well as test performance.
Explanation:
Positive predictive value depends on disease prevalence as well as test performance.
Choose an option to check your answer.
A.
It prevents every adverse effect.
B.
It is identical to an intravenous bolus.
C.
It guarantees immediate peak concentration.
D.
A depot formulation can prolong drug release and reduce dosing frequency.
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Correct Answer: D. A depot formulation can prolong drug release and reduce dosing frequency.
Explanation:
A depot formulation can prolong drug release and reduce dosing frequency.
Choose an option to check your answer.
A.
2620.8
B.
0.024
C.
45.5
D.
40.95
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Correct Answer: D. 40.95
Explanation:
Apply AUC=F×Dose/CL.
Choose an option to check your answer.
A.
12.5
B.
50
C.
6.25
D.
25
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Correct Answer: A. 12.5
Explanation:
After three half-lives, (1/2)^3=12.5%.
Choose an option to check your answer.
A.
It removes the need for agonist binding.
B.
It irreversibly increases efficacy.
C.
It always raises the maximal response.
D.
A competitive antagonist usually shifts the agonist concentration–response curve to the right without reducing the maximal response.
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Correct Answer: D. A competitive antagonist usually shifts the agonist concentration–response curve to the right without reducing the maximal response.
Explanation:
A competitive antagonist usually shifts the agonist concentration–response curve to the right without reducing the maximal response.
Choose an option to check your answer.
A.
Reducing particle size can increase dissolution rate by increasing surface area.
B.
It always decreases surface area.
C.
It guarantees chemical stability.
D.
It eliminates first-pass metabolism.
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Correct Answer: A. Reducing particle size can increase dissolution rate by increasing surface area.
Explanation:
Reducing particle size can increase dissolution rate by increasing surface area.
Choose an option to check your answer.
A.
0.1
B.
1.0
C.
6.6
D.
10.0
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Correct Answer: D. 10.0
Explanation:
For a weak acid, [A−]/[HA]=10^(pH−pKa).
Choose an option to check your answer.
A.
Bactericidal agents cannot have resistance.
B.
Bacteriostatic agents always destroy spores.
C.
Bactericidal activity kills susceptible bacteria, whereas bacteriostatic activity inhibits growth.
D.
Both terms mean viral inactivation.
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Correct Answer: C. Bactericidal activity kills susceptible bacteria, whereas bacteriostatic activity inhibits growth.
Explanation:
Bactericidal activity kills susceptible bacteria, whereas bacteriostatic activity inhibits growth.
Choose an option to check your answer.
A.
14018
B.
0.132
C.
7.58
D.
9.58
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Correct Answer: C. 7.58
Explanation:
Concentration=amount/volume.
Choose an option to check your answer.
A.
It removes the need for agonist binding.
B.
It always raises the maximal response.
C.
A competitive antagonist usually shifts the agonist concentration–response curve to the right without reducing the maximal response.
D.
It irreversibly increases efficacy.
Show Answer
Correct Answer: C. A competitive antagonist usually shifts the agonist concentration–response curve to the right without reducing the maximal response.
Explanation:
A competitive antagonist usually shifts the agonist concentration–response curve to the right without reducing the maximal response.
Choose an option to check your answer.
A.
It guarantees chemical stability.
B.
Reducing particle size can increase dissolution rate by increasing surface area.
C.
It eliminates first-pass metabolism.
D.
It always decreases surface area.
Show Answer
Correct Answer: B. Reducing particle size can increase dissolution rate by increasing surface area.
Explanation:
Reducing particle size can increase dissolution rate by increasing surface area.
Choose an option to check your answer.
A.
10.0
B.
4.2
C.
1.0
D.
0.1
Show Answer
Correct Answer: A. 10.0
Explanation:
For a weak acid, [A−]/[HA]=10^(pH−pKa).
