MCQ Collection
opra MCQs
Practice opra questions with answers and explanations.
Choose an option to check your answer.
A.
It always decreases surface area.
B.
It guarantees chemical stability.
C.
Reducing particle size can increase dissolution rate by increasing surface area.
D.
It eliminates first-pass metabolism.
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Correct Answer: C. Reducing particle size can increase dissolution rate by increasing surface area.
Explanation:
Reducing particle size can increase dissolution rate by increasing surface area.
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A.
Phase I reactions commonly introduce or expose functional groups through oxidation, reduction or hydrolysis.
B.
Phase I is limited to renal filtration.
C.
Phase I reactions occur only outside the body.
D.
Phase I always produces an inactive metabolite.
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Correct Answer: A. Phase I reactions commonly introduce or expose functional groups through oxidation, reduction or hydrolysis.
Explanation:
Phase I reactions commonly introduce or expose functional groups through oxidation, reduction or hydrolysis.
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A.
Randomisation guarantees zero measurement error.
B.
Blinding always increases sample size.
C.
A case report proves population causality.
D.
A randomised controlled design reduces allocation bias and supports causal inference when well conducted.
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Correct Answer: D. A randomised controlled design reduces allocation bias and supports causal inference when well conducted.
Explanation:
A randomised controlled design reduces allocation bias and supports causal inference when well conducted.
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A.
It must be 100% when specificity is above 50%.
B.
It is always equal to sensitivity.
C.
Positive predictive value depends on disease prevalence as well as test performance.
D.
It is independent of prevalence.
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Correct Answer: C. Positive predictive value depends on disease prevalence as well as test performance.
Explanation:
Positive predictive value depends on disease prevalence as well as test performance.
Choose an option to check your answer.
A.
A depot formulation can prolong drug release and reduce dosing frequency.
B.
It is identical to an intravenous bolus.
C.
It guarantees immediate peak concentration.
D.
It prevents every adverse effect.
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Correct Answer: A. A depot formulation can prolong drug release and reduce dosing frequency.
Explanation:
A depot formulation can prolong drug release and reduce dosing frequency.
Choose an option to check your answer.
A.
46978
B.
6.82
C.
0.147
D.
8.82
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Correct Answer: B. 6.82
Explanation:
Concentration=amount/volume.
Choose an option to check your answer.
A.
39.6
B.
4791.6
C.
44.0
D.
0.025
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Correct Answer: A. 39.6
Explanation:
Apply AUC=F×Dose/CL.
Choose an option to check your answer.
A.
12.5
B.
25
C.
6.25
D.
50
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Correct Answer: A. 12.5
Explanation:
After three half-lives, (1/2)^3=12.5%.
Choose an option to check your answer.
A.
It irreversibly increases efficacy.
B.
It always raises the maximal response.
C.
A competitive antagonist usually shifts the agonist concentration–response curve to the right without reducing the maximal response.
D.
It removes the need for agonist binding.
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Correct Answer: C. A competitive antagonist usually shifts the agonist concentration–response curve to the right without reducing the maximal response.
Explanation:
A competitive antagonist usually shifts the agonist concentration–response curve to the right without reducing the maximal response.
Choose an option to check your answer.
A.
It guarantees chemical stability.
B.
It eliminates first-pass metabolism.
C.
It always decreases surface area.
D.
Reducing particle size can increase dissolution rate by increasing surface area.
Show Answer
Correct Answer: D. Reducing particle size can increase dissolution rate by increasing surface area.
Explanation:
Reducing particle size can increase dissolution rate by increasing surface area.
Choose an option to check your answer.
A.
6.6
B.
1.0
C.
10.0
D.
0.1
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Correct Answer: C. 10.0
Explanation:
For a weak acid, [A−]/[HA]=10^(pH−pKa).
Choose an option to check your answer.
A.
Bactericidal agents cannot have resistance.
B.
Bacteriostatic agents always destroy spores.
C.
Both terms mean viral inactivation.
D.
Bactericidal activity kills susceptible bacteria, whereas bacteriostatic activity inhibits growth.
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Correct Answer: D. Bactericidal activity kills susceptible bacteria, whereas bacteriostatic activity inhibits growth.
Explanation:
Bactericidal activity kills susceptible bacteria, whereas bacteriostatic activity inhibits growth.
