MCQ Collection
opra MCQs
Practice opra questions with answers and explanations.
Choose an option to check your answer.
A.
3964.8
B.
0.036
C.
39.33
D.
27.53
Show Answer
Correct Answer: D. 27.53
Explanation:
Apply AUC=F×Dose/CL.
Choose an option to check your answer.
A.
12.5
B.
6.25
C.
50
D.
25
Show Answer
Correct Answer: A. 12.5
Explanation:
After three half-lives, (1/2)^3=12.5%.
Choose an option to check your answer.
A.
It irreversibly increases efficacy.
B.
It always raises the maximal response.
C.
A competitive antagonist usually shifts the agonist concentration–response curve to the right without reducing the maximal response.
D.
It removes the need for agonist binding.
Show Answer
Correct Answer: C. A competitive antagonist usually shifts the agonist concentration–response curve to the right without reducing the maximal response.
Explanation:
A competitive antagonist usually shifts the agonist concentration–response curve to the right without reducing the maximal response.
Choose an option to check your answer.
A.
8.78
B.
10.78
C.
0.114
D.
30562
Show Answer
Correct Answer: A. 8.78
Explanation:
Concentration=amount/volume.
Choose an option to check your answer.
A.
2990.0
B.
35.38
C.
0.057
D.
17.69
Show Answer
Correct Answer: D. 17.69
Explanation:
Apply AUC=F×Dose/CL.
Choose an option to check your answer.
A.
25
B.
50
C.
12.5
D.
6.25
Show Answer
Correct Answer: C. 12.5
Explanation:
After three half-lives, (1/2)^3=12.5%.
Choose an option to check your answer.
A.
It removes the need for agonist binding.
B.
It irreversibly increases efficacy.
C.
It always raises the maximal response.
D.
A competitive antagonist usually shifts the agonist concentration–response curve to the right without reducing the maximal response.
Show Answer
Correct Answer: D. A competitive antagonist usually shifts the agonist concentration–response curve to the right without reducing the maximal response.
Explanation:
A competitive antagonist usually shifts the agonist concentration–response curve to the right without reducing the maximal response.
Choose an option to check your answer.
A.
It guarantees chemical stability.
B.
Reducing particle size can increase dissolution rate by increasing surface area.
C.
It eliminates first-pass metabolism.
D.
It always decreases surface area.
Show Answer
Correct Answer: B. Reducing particle size can increase dissolution rate by increasing surface area.
Explanation:
Reducing particle size can increase dissolution rate by increasing surface area.
Choose an option to check your answer.
A.
1.0
B.
0.1
C.
10.0
D.
4.8
Show Answer
Correct Answer: C. 10.0
Explanation:
For a weak acid, [A−]/[HA]=10^(pH−pKa).
Choose an option to check your answer.
A.
99.6
B.
42.0
C.
65.7
D.
152.2
Show Answer
Correct Answer: C. 65.7
Explanation:
Use fraction remaining=e^(−kt).
Choose an option to check your answer.
A.
Blinding always increases sample size.
B.
A randomised controlled design reduces allocation bias and supports causal inference when well conducted.
C.
Randomisation guarantees zero measurement error.
D.
A case report proves population causality.
Show Answer
Correct Answer: B. A randomised controlled design reduces allocation bias and supports causal inference when well conducted.
Explanation:
A randomised controlled design reduces allocation bias and supports causal inference when well conducted.
Choose an option to check your answer.
A.
It is always equal to sensitivity.
B.
It is independent of prevalence.
C.
Positive predictive value depends on disease prevalence as well as test performance.
D.
It must be 100% when specificity is above 50%.
Show Answer
Correct Answer: C. Positive predictive value depends on disease prevalence as well as test performance.
Explanation:
Positive predictive value depends on disease prevalence as well as test performance.
