MCQ Collection
opra MCQs
Practice opra questions with answers and explanations.
Choose an option to check your answer.
A.
A case report proves population causality.
B.
Randomisation guarantees zero measurement error.
C.
A randomised controlled design reduces allocation bias and supports causal inference when well conducted.
D.
Blinding always increases sample size.
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Correct Answer: C. A randomised controlled design reduces allocation bias and supports causal inference when well conducted.
Explanation:
A randomised controlled design reduces allocation bias and supports causal inference when well conducted.
Choose an option to check your answer.
A.
10.0
B.
6.0
C.
0.1
D.
1.0
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Correct Answer: A. 10.0
Explanation:
For a weak acid, [A−]/[HA]=10^(pH−pKa).
Choose an option to check your answer.
A.
Bactericidal activity kills susceptible bacteria, whereas bacteriostatic activity inhibits growth.
B.
Both terms mean viral inactivation.
C.
Bacteriostatic agents always destroy spores.
D.
Bactericidal agents cannot have resistance.
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Correct Answer: A. Bactericidal activity kills susceptible bacteria, whereas bacteriostatic activity inhibits growth.
Explanation:
Bactericidal activity kills susceptible bacteria, whereas bacteriostatic activity inhibits growth.
Choose an option to check your answer.
A.
Phase I reactions commonly introduce or expose functional groups through oxidation, reduction or hydrolysis.
B.
Phase I reactions occur only outside the body.
C.
Phase I always produces an inactive metabolite.
D.
Phase I is limited to renal filtration.
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Correct Answer: A. Phase I reactions commonly introduce or expose functional groups through oxidation, reduction or hydrolysis.
Explanation:
Phase I reactions commonly introduce or expose functional groups through oxidation, reduction or hydrolysis.
Choose an option to check your answer.
A.
3924.0
B.
29.07
C.
17.44
D.
0.057
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Correct Answer: C. 17.44
Explanation:
Apply AUC=F×Dose/CL.
Choose an option to check your answer.
A.
12.5
B.
6.25
C.
50
D.
25
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Correct Answer: A. 12.5
Explanation:
After three half-lives, (1/2)^3=12.5%.
Choose an option to check your answer.
A.
It removes the need for agonist binding.
B.
A competitive antagonist usually shifts the agonist concentration–response curve to the right without reducing the maximal response.
C.
It always raises the maximal response.
D.
It irreversibly increases efficacy.
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Correct Answer: B. A competitive antagonist usually shifts the agonist concentration–response curve to the right without reducing the maximal response.
Explanation:
A competitive antagonist usually shifts the agonist concentration–response curve to the right without reducing the maximal response.
Choose an option to check your answer.
A.
Reducing particle size can increase dissolution rate by increasing surface area.
B.
It eliminates first-pass metabolism.
C.
It always decreases surface area.
D.
It guarantees chemical stability.
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Correct Answer: A. Reducing particle size can increase dissolution rate by increasing surface area.
Explanation:
Reducing particle size can increase dissolution rate by increasing surface area.
Choose an option to check your answer.
A.
Reducing particle size can increase dissolution rate by increasing surface area.
B.
It always decreases surface area.
C.
It guarantees chemical stability.
D.
It eliminates first-pass metabolism.
Show Answer
Correct Answer: A. Reducing particle size can increase dissolution rate by increasing surface area.
Explanation:
Reducing particle size can increase dissolution rate by increasing surface area.
Choose an option to check your answer.
A.
0.1
B.
10.0
C.
6.6
D.
1.0
Show Answer
Correct Answer: B. 10.0
Explanation:
For a weak acid, [A−]/[HA]=10^(pH−pKa).
Choose an option to check your answer.
A.
Both terms mean viral inactivation.
B.
Bactericidal agents cannot have resistance.
C.
Bactericidal activity kills susceptible bacteria, whereas bacteriostatic activity inhibits growth.
D.
Bacteriostatic agents always destroy spores.
Show Answer
Correct Answer: C. Bactericidal activity kills susceptible bacteria, whereas bacteriostatic activity inhibits growth.
Explanation:
Bactericidal activity kills susceptible bacteria, whereas bacteriostatic activity inhibits growth.
Choose an option to check your answer.
A.
Phase I reactions commonly introduce or expose functional groups through oxidation, reduction or hydrolysis.
B.
Phase I always produces an inactive metabolite.
C.
Phase I reactions occur only outside the body.
D.
Phase I is limited to renal filtration.
Show Answer
Correct Answer: A. Phase I reactions commonly introduce or expose functional groups through oxidation, reduction or hydrolysis.
Explanation:
Phase I reactions commonly introduce or expose functional groups through oxidation, reduction or hydrolysis.
