MCQ Collection
opra MCQs
Practice opra questions with answers and explanations.
Choose an option to check your answer.
A.
It is identical to an intravenous bolus.
B.
It guarantees immediate peak concentration.
C.
A depot formulation can prolong drug release and reduce dosing frequency.
D.
It prevents every adverse effect.
Show Answer
Correct Answer: C. A depot formulation can prolong drug release and reduce dosing frequency.
Explanation:
A depot formulation can prolong drug release and reduce dosing frequency.
Choose an option to check your answer.
A.
It is independent of prevalence.
B.
It must be 100% when specificity is above 50%.
C.
Positive predictive value depends on disease prevalence as well as test performance.
D.
It is always equal to sensitivity.
Show Answer
Correct Answer: C. Positive predictive value depends on disease prevalence as well as test performance.
Explanation:
Positive predictive value depends on disease prevalence as well as test performance.
Choose an option to check your answer.
A.
It guarantees immediate peak concentration.
B.
A depot formulation can prolong drug release and reduce dosing frequency.
C.
It prevents every adverse effect.
D.
It is identical to an intravenous bolus.
Show Answer
Correct Answer: B. A depot formulation can prolong drug release and reduce dosing frequency.
Explanation:
A depot formulation can prolong drug release and reduce dosing frequency.
Choose an option to check your answer.
A.
10.51
B.
23218
C.
0.095
D.
12.51
Show Answer
Correct Answer: A. 10.51
Explanation:
Concentration=amount/volume.
Choose an option to check your answer.
A.
5017.6
B.
0.039
C.
32.0
D.
25.6
Show Answer
Correct Answer: D. 25.6
Explanation:
Apply AUC=F×Dose/CL.
Choose an option to check your answer.
A.
6.25
B.
25
C.
12.5
D.
50
Show Answer
Correct Answer: C. 12.5
Explanation:
After three half-lives, (1/2)^3=12.5%.
Choose an option to check your answer.
A.
It irreversibly increases efficacy.
B.
It always raises the maximal response.
C.
A competitive antagonist usually shifts the agonist concentration–response curve to the right without reducing the maximal response.
D.
It removes the need for agonist binding.
Show Answer
Correct Answer: C. A competitive antagonist usually shifts the agonist concentration–response curve to the right without reducing the maximal response.
Explanation:
A competitive antagonist usually shifts the agonist concentration–response curve to the right without reducing the maximal response.
Choose an option to check your answer.
A.
It always decreases surface area.
B.
It guarantees chemical stability.
C.
Reducing particle size can increase dissolution rate by increasing surface area.
D.
It eliminates first-pass metabolism.
Show Answer
Correct Answer: C. Reducing particle size can increase dissolution rate by increasing surface area.
Explanation:
Reducing particle size can increase dissolution rate by increasing surface area.
Choose an option to check your answer.
A.
10.0
B.
1.0
C.
5.4
D.
0.1
Show Answer
Correct Answer: A. 10.0
Explanation:
For a weak acid, [A−]/[HA]=10^(pH−pKa).
Choose an option to check your answer.
A.
Both terms mean viral inactivation.
B.
Bacteriostatic agents always destroy spores.
C.
Bactericidal agents cannot have resistance.
D.
Bactericidal activity kills susceptible bacteria, whereas bacteriostatic activity inhibits growth.
Show Answer
Correct Answer: D. Bactericidal activity kills susceptible bacteria, whereas bacteriostatic activity inhibits growth.
Explanation:
Bactericidal activity kills susceptible bacteria, whereas bacteriostatic activity inhibits growth.
Choose an option to check your answer.
A.
Phase I always produces an inactive metabolite.
B.
Phase I reactions commonly introduce or expose functional groups through oxidation, reduction or hydrolysis.
C.
Phase I reactions occur only outside the body.
D.
Phase I is limited to renal filtration.
Show Answer
Correct Answer: B. Phase I reactions commonly introduce or expose functional groups through oxidation, reduction or hydrolysis.
Explanation:
Phase I reactions commonly introduce or expose functional groups through oxidation, reduction or hydrolysis.
Choose an option to check your answer.
A.
57.6
B.
173.7
C.
99.4
D.
55.2
Show Answer
Correct Answer: A. 57.6
Explanation:
Use fraction remaining=e^(−kt).
