MCQ Collection
OPRA Pharmaceutical Sciences MCQs
Practice OPRA Pharmaceutical Sciences questions with answers and explanations.
Choose an option to check your answer.
A.
It always raises the maximal response.
B.
It removes the need for agonist binding.
C.
A competitive antagonist usually shifts the agonist concentration–response curve to the right without reducing the maximal response.
D.
It irreversibly increases efficacy.
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Correct Answer: C. A competitive antagonist usually shifts the agonist concentration–response curve to the right without reducing the maximal response.
Explanation:
A competitive antagonist usually shifts the agonist concentration–response curve to the right without reducing the maximal response.
Choose an option to check your answer.
A.
It guarantees chemical stability.
B.
Reducing particle size can increase dissolution rate by increasing surface area.
C.
It eliminates first-pass metabolism.
D.
It always decreases surface area.
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Correct Answer: B. Reducing particle size can increase dissolution rate by increasing surface area.
Explanation:
Reducing particle size can increase dissolution rate by increasing surface area.
Choose an option to check your answer.
A.
1.0
B.
5.4
C.
10.0
D.
0.1
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Correct Answer: C. 10.0
Explanation:
For a weak acid, [A−]/[HA]=10^(pH−pKa).
Choose an option to check your answer.
A.
Bactericidal agents cannot have resistance.
B.
Both terms mean viral inactivation.
C.
Bactericidal activity kills susceptible bacteria, whereas bacteriostatic activity inhibits growth.
D.
Bacteriostatic agents always destroy spores.
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Correct Answer: C. Bactericidal activity kills susceptible bacteria, whereas bacteriostatic activity inhibits growth.
Explanation:
Bactericidal activity kills susceptible bacteria, whereas bacteriostatic activity inhibits growth.
Choose an option to check your answer.
A.
Phase I is limited to renal filtration.
B.
Phase I reactions commonly introduce or expose functional groups through oxidation, reduction or hydrolysis.
C.
Phase I always produces an inactive metabolite.
D.
Phase I reactions occur only outside the body.
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Correct Answer: B. Phase I reactions commonly introduce or expose functional groups through oxidation, reduction or hydrolysis.
Explanation:
Phase I reactions commonly introduce or expose functional groups through oxidation, reduction or hydrolysis.
Choose an option to check your answer.
A.
84.0
B.
231.6
C.
99.2
D.
43.2
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Correct Answer: D. 43.2
Explanation:
Use fraction remaining=e^(−kt).
Choose an option to check your answer.
A.
0.044
B.
24.74
C.
16578
D.
22.74
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Correct Answer: D. 22.74
Explanation:
Concentration=amount/volume.
Choose an option to check your answer.
A.
9.6
B.
777.6
C.
0.104
D.
12.0
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Correct Answer: A. 9.6
Explanation:
Apply AUC=F×Dose/CL.
Choose an option to check your answer.
A.
12.5
B.
6.25
C.
25
D.
50
Show Answer
Correct Answer: A. 12.5
Explanation:
After three half-lives, (1/2)^3=12.5%.
Choose an option to check your answer.
A.
10.0
B.
1.0
C.
6.0
D.
0.1
Show Answer
Correct Answer: A. 10.0
Explanation:
For a weak acid, [A−]/[HA]=10^(pH−pKa).
Choose an option to check your answer.
A.
Bactericidal activity kills susceptible bacteria, whereas bacteriostatic activity inhibits growth.
B.
Both terms mean viral inactivation.
C.
Bacteriostatic agents always destroy spores.
D.
Bactericidal agents cannot have resistance.
Show Answer
Correct Answer: A. Bactericidal activity kills susceptible bacteria, whereas bacteriostatic activity inhibits growth.
Explanation:
Bactericidal activity kills susceptible bacteria, whereas bacteriostatic activity inhibits growth.
Choose an option to check your answer.
A.
Phase I is limited to renal filtration.
B.
Phase I reactions commonly introduce or expose functional groups through oxidation, reduction or hydrolysis.
C.
Phase I always produces an inactive metabolite.
D.
Phase I reactions occur only outside the body.
Show Answer
Correct Answer: B. Phase I reactions commonly introduce or expose functional groups through oxidation, reduction or hydrolysis.
Explanation:
Phase I reactions commonly introduce or expose functional groups through oxidation, reduction or hydrolysis.
